dihydrofolate reductase activity [GO_0004146]
Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+.
dihydrofolate reductase activity
ID: GO_0004146
Class
Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+.
Open in VFB 3D Browser →Classification
Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| DHFR | related synonym | 1.5.1.3 |
| pteridine reductase:dihydrofolate reductase activity | related synonym | 1.5.1.3 |
| folic acid reductase activity | related synonym | 1.5.1.3 |
| folic reductase activity | related synonym | 1.5.1.3 |
| thymidylate synthetase-dihydrofolate reductase activity | related synonym | 1.5.1.3 |
| 7,8-dihydrofolate reductase activity | related synonym | 1.5.1.3 |
| dihydrofolate reductase:thymidylate synthase activity | related synonym | 1.5.1.3 |
| tetrahydrofolate dehydrogenase activity | related synonym | 1.5.1.3 |
| 5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase activity | related synonym | 1.5.1.3 |
| NADPH-dihydrofolate reductase activity | related synonym | 1.5.1.3 |
| dihydrofolic acid reductase activity | related synonym | 1.5.1.3 |
| dihydrofolic reductase activity | related synonym | 1.5.1.3 |
| dihydrofolate reduction | exact synonym |
References
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