INR_motif [SO_0000014]
A sequence element characteristic of some RNA polymerase II promoters required for the correct positioning of the polymerase for the start of transcription. Overlaps the TSS. The mammalian consensus sequence is YYAN(T|A)YY; the Drosophila consensus sequence is TCA(G|T)t(T|C). In each the A is at position +1 with respect to the TSS. Functionally similar to the TATA box element.
INR_motif
ID: SO_0000014
Class
A sequence element characteristic of some RNA polymerase II promoters required for the correct positioning of the polymerase for the start of transcription. Overlaps the TSS. The mammalian consensus sequence is YYAN(T|A)YY; the Drosophila consensus sequence is TCA(G|T)t(T|C). In each the A is at position +1 with respect to the TSS. Functionally similar to the TATA box element.
Binds TAF1, TAF2.
Open in VFB 3D Browser →Classification
Relationships
- is part of: RNApol_II_core_promoter
Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| INR motif | exact synonym | |
| initiator | exact synonym | |
| initiator motif | exact synonym | |
| DMp2 | related synonym |
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