melanotic mass phenotype [FBcv_0000446]
Phenotype characterized by the formation of lumps of melanotic tissue inside the body in the absence of foreign bodies. Melanotic capsules are formed around foreign bodies in wild-type animals as part of the immune response, for example as a protection against parasitoid wasps. Some, but not all melanotic mass phenotypes involve ectopic activation of this immune response. While melanotic masses are commonly referred to as melanotic tumors in the historical literature, this is a misnomer as they are rarely neoplastic.
Note
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VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/FBcv_0000446",
"symbol": "",
"types": [
"Entity",
"Class"
],
"short_form": "FBcv_0000446",
"label": "melanotic mass phenotype"
},
"description": [
"Phenotype characterized by the formation of lumps of melanotic tissue inside the body in the absence of foreign bodies."
],
"comment": [
"Melanotic capsules are formed around foreign bodies in wild-type animals as part of the immune response, for example as a protection against parasitoid wasps. Some, but not all melanotic mass phenotypes involve ectopic activation of this immune response. While melanotic masses are commonly referred to as melanotic tumors in the historical literature, this is a misnomer as they are rarely neoplastic."
]
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBcv_0001347",
"types": [
"Entity",
"Class"
],
"short_form": "FBcv_0001347",
"label": "phenotype"
}
],
"relationships": [],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_exact_synonym",
"label": "melanotic 'tumor'",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": [
{
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/FBrf0194475",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "FBrf0194475",
"label": "Minakhina and Steward, 2006, Genetics 174(1): 253--263"
},
"FlyBase": "",
"PubMed": "16816412",
"DOI": "10.1534/genetics.106.061978"
},
{
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/FBrf0094387",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "FBrf0094387",
"label": "Carton and Nappi, 1997, Parasitology Today 13(6): 218--227"
},
"FlyBase": "",
"PubMed": "15275074",
"DOI": "10.1016/S0169-4758(97)01058-2"
}
]
}
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